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salivarius HN26-4, NT4-8, and FXJCJ7-2) that were clearly categorized in different sub-phylotypes of the phylogenetic tree were randomly selected for further studies. Compared to the other two tested strains, 2019-01-15 2019-03-26 Short half-life of HPV16 E6 and E7 mRNAs sensitizes HPV16-positive tonsillar cancer cell line HN26 to DNA-damaging drugs. Forskningsoutput: Tidskriftsbidrag › Artikel i vetenskaplig tidskrift Here we show that treatment of the HPV16-positive tonsillar cancer cell line HN26 with DNA alkylating cancer drug melphalan-induced p53 and activated apoptosis. Melphalan reduced the levels of RNA polymerase II and cellular transcription factor Sp1 that were associated with HPV16 DNA. The resulting inhibition of transcription caused a rapid loss of the HPV16 early mRNAs encoding E6 and E7 as a The HN26 cell line (full name LU‐HNSCC‐26) was isolated from a 48‐year‐old nonsmoking man diagnosed with poorly differentiated, p16‐positive squamous cell tonsillar carcinoma stage T2N0M0 with HPV16 and has been previously described (Table 1). 31 The C33A2 cell line is derived from the HPV‐negative and p53‐negative cervical cancer Buy Nikon HN-26 Hood for the ORIGINAL Nikon 62mm Circular Polarizing Filter featuring This Hood Will Not Fit the Current Nikon 62mm Polarizer. Review Nikon HN-26 HN26/SNL SKF Hook Spanner Unique design allows the SKF HN5/SNL series to be used inside SKF SNL and SNH bearing housings Suitable for tightening and loosening a wide selection of lock nuts, facilitating their use in a wide range of housing and shaft applications The BARD1‐negative phenotype of the HN26 cells may have contributed to the failure to repair DNA damage caused by melphalan, as well as to the efficient apoptosis induction.
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